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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARFIP2
All Species:
43.94
Human Site:
T221
Identified Species:
80.56
UniProt:
P53365
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53365
NP_036534.1
341
37856
T221
V
T
K
T
M
E
D
T
L
M
T
V
K
Q
Y
Chimpanzee
Pan troglodytes
XP_001165725
341
37811
T221
V
T
K
T
M
E
D
T
L
M
T
V
K
Q
Y
Rhesus Macaque
Macaca mulatta
XP_001109657
341
37821
T221
V
T
K
T
M
E
D
T
L
M
T
V
K
Q
Y
Dog
Lupus familis
XP_850974
341
37722
T221
V
T
K
T
M
E
D
T
L
M
T
V
K
Q
Y
Cat
Felis silvestris
Mouse
Mus musculus
NP_001074562
373
41500
T253
V
N
K
T
I
E
D
T
L
M
T
V
K
Q
Y
Rat
Rattus norvegicus
Q6AY65
341
37754
T221
V
T
K
T
M
E
D
T
L
M
T
V
K
Q
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517148
301
33210
L199
L
C
K
N
G
E
T
L
L
G
A
V
N
F
F
Chicken
Gallus gallus
XP_001233078
373
41527
T253
V
N
K
T
I
E
D
T
L
L
T
V
K
Q
Y
Frog
Xenopus laevis
NP_001080149
342
38707
T222
V
N
K
T
I
E
D
T
L
I
T
V
K
Q
Y
Zebra Danio
Brachydanio rerio
NP_001017649
355
40140
T235
V
N
K
T
M
E
D
T
L
M
T
I
K
M
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396054
330
37364
T210
C
N
K
T
I
E
D
T
L
F
T
V
R
Q
Y
Nematode Worm
Caenorhab. elegans
P34445
307
33896
T198
T
L
H
T
I
Y
N
T
E
S
A
R
I
E
Y
Sea Urchin
Strong. purpuratus
XP_787151
403
44835
T283
C
N
K
T
M
E
D
T
L
L
T
V
K
A
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.7
99.4
N.A.
53.6
99.1
N.A.
80
52.5
57
73.8
N.A.
N.A.
51.3
29.6
47.6
Protein Similarity:
100
99.7
100
99.7
N.A.
70.2
99.4
N.A.
84.4
69.4
75.4
85
N.A.
N.A.
68.3
49.5
61.7
P-Site Identity:
100
100
100
100
N.A.
86.6
100
N.A.
26.6
80
80
80
N.A.
N.A.
66.6
20
73.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
40
93.3
93.3
86.6
N.A.
N.A.
80
40
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
16
0
0
8
0
% A
% Cys:
16
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
85
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
93
0
0
8
0
0
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
8
% F
% Gly:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
39
0
0
0
0
8
0
8
8
0
0
% I
% Lys:
0
0
93
0
0
0
0
0
0
0
0
0
77
0
0
% K
% Leu:
8
8
0
0
0
0
0
8
93
16
0
0
0
0
0
% L
% Met:
0
0
0
0
54
0
0
0
0
54
0
0
0
8
0
% M
% Asn:
0
47
0
8
0
0
8
0
0
0
0
0
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
70
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% S
% Thr:
8
39
0
93
0
0
8
93
0
0
85
0
0
0
0
% T
% Val:
70
0
0
0
0
0
0
0
0
0
0
85
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
93
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _